Homosexuality genetics

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Ever since Charles Darwin taught us that we are just another species in the natural order, science has tried to unravel what specifically makes us human, what we all have in common. But at the same time, scientists continue to investigate what makes us diverse, from physical traits or personality to our sexual orientation. And while much remains to be learned about the latter, modern science suggests that it is a complex interaction of biological factors that determines whether we are attracted to people of our own sex, the opposite sex, or both. In , Science published a study by the U. National Institutes of Health that found in 40 pairs of siblings a relationship between male homosexuality and a certain region of the X sex chromosome. However, further research failed to confirm this presumed finding.
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Biology and sexual orientation

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Is homosexuality genetic? A critical review and some suggestions

A genetic analysis of almost half a million people has concluded there is no single "gay gene". The study, published in Science , used data from the UK Biobank and 23andMe, and found some genetic variants associated with same-sex relationships. Advocacy group GLAAD said the study confirmed "no conclusive degree to which nature or nurture influenced how a gay or lesbian person behaves. The researchers scanned the genomes - the entire genetic make-up - of , people signed up to the UK Biobank project, and 68, registered with the genetics company 23andMe. Participants were also asked whether they had same-sex partners exclusively, or as well as opposite-sex partners. Five specific genetic variants were found to be particularly associated with same-sex behaviour, including one linked to the biological pathway for smell, and others to those for sex hormones.
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Is Our Sexual Orientation Determined by Biology?

Few aspects of human biology are as complex—or politically fraught—as sexual orientation. Now, a new study claims to dispel the notion that a single gene or handful of genes make a person prone to same-sex behavior. The analysis, which examined the genomes of nearly half a million men and women, found that although genetics are certainly involved in who people choose to have sex with, there are no specific genetic predictors. Yet some researchers question whether the analysis, which looked at genes associated with sexual activity rather than attraction, can draw any real conclusions about sexual orientation. The handful of genetic studies conducted in the past few decades have looked at only a few hundred individuals at most—and almost exclusively men.
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The relationship between biology and sexual orientation is a subject of research. While scientists do not know the exact cause of sexual orientation , they theorize that it is caused by a complex interplay of genetic , hormonal , and environmental influences. Biological theories for explaining the causes of sexual orientation are favored by scientists. The influence of hormones on the developing foetus has been the most influential causal hypothesis of the development of sexual orientation. The presence of the Y-chromosome in males prompts the development of testes, which release testosterone, the primary androgen receptor-activating hormone, to masculinize the fetus and fetal brain.
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